human KIRREL3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KIRREL3.
shAAV-213149
AAV-h-KIRREL3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KIRREL3 (kin of IRRE like 3 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
KIRRE; MRD4; NEPH2; PRO4502
Description (Vector)
KIRREL3 is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
84623
Gene Name (Vector)
kin of IRRE like 3 (Drosophila)
Gene Symbol
KIRREL3
HGNC ID
HGNC:23204
ORF Size (aa)
2337
ORF Size (bp)
2337 bp
RefSeq ID
NM_032531
RefSeq Synonyms
NM_032531, NM_001301097, NM_001161707, BC101801, BC101775,
Species
human
UniGene ID
Hs.657065
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.