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human KIAA0430 shRNA silencing AAV

Name 
AAV-h-KIAA0430-shRNA
Cat No 
shAAV-212916
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KIAA0430.

shAAV-212916
AAV-h-KIAA0430-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KIAA0430 (KIAA0430). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KIAA0430; limkain-b1; LKAP; LMKB; meiosis arrest female 1; meiosis arrest female protein 1; meiosis regulator and mRNA stability factor 1; PPP1R34; protein phosphatase 1, regulatory subunit 34
Description (eCommerce)
Limkain b1 is an essential regulator of oogenesis required for female meiotic progression. Limkain b1 acts by down-regulating RNA transcripts, either at transcriptional of post-transcriptional level (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y4F3].
Description (Vector)
KIAA0430 encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic.
Gene ID
9665
Gene Name (eCommerce)
meiosis regulator and mRNA stability factor 1
Gene Name (Vector)
KIAA0430
Gene Symbol
KIAA0430
HGNC ID
HGNC:29562
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5220
ORF Size (bp)
5220 bp
Protein Name (eCommerce)
Meiosis arrest female protein 1
RefSeq ID
NM_014647
RefSeq Synonyms
NM_014647, NM_001184999, NM_001184998, BC144515, BC144514, BC137170, BC137165,
Research Areas
Cell Biology,Cell Cycle,Gene Expression,Meiosis,Phosphatase,RNA Binding,RNA Processing,Translational Control,Ubiquitination
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
Limkain b1 is an essential regulator of oogenesis required for female meiotic progression. Limkain b1 acts by down-regulating RNA transcripts, either at transcriptional of post-transcriptional level (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y4F3].
UniGene ID
Hs.173524
UniProt ID (eCommerce)
Q9Y4F3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.