human KIAA0020 shRNA silencing AAV

Name 
AAV-h-KIAA0020-shRNA
Cat No 
shAAV-212879
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PUM3.

shAAV-212879
AAV-h-KIAA0020-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PUM3 (pumilio RNA binding family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HA-8; HBV XAg-transactivated protein 5; HBV X-transactivated gene 5 protein; HLA-HA8; KIAA0020; minor histocompatibility antigen HA-8; PEN; penguin homolog; protein 5 transactivated by hepatitis B virus X antigen (HBxAg); PUF6; PUF-A; pumilio homolog 3; XTP5
Description (eCommerce)
KIAA0020 is also known as human Puf-A (hPuf-A). KIAA0020 may play a role in the response to genotoxic stress by regulating PARP-1 activity.
Gene ID
9933
Gene Name (eCommerce)
pumilio RNA binding family member 3
Gene Name (Vector)
pumilio RNA binding family member 3
Gene Symbol
PUM3
HGNC ID
HGNC:29676
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1947
ORF Size (bp)
1947 bp
Protein Name (eCommerce)
Pumilio homolog 3
RefSeq ID
NM_014878
RefSeq Synonyms
NM_014878, BC016137,
Research Areas
Cell Biology,DNA Damage/Repair,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
KIAA0020 is also known as human Puf-A (hPuf-A). KIAA0020 may play a role in the response to genotoxic stress by regulating PARP-1 activity.
UniGene ID
Hs.493309
UniProt ID (eCommerce)
Q15397

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.