human KCNS1 shRNA silencing AAV

Name
AAV-h-KCNS1-shRNA

Cat No
shAAV-212778

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNS1.

shAAV-212778

AAV-h-KCNS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNS1 (potassium voltage-gated channel modifier subfamily S member 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Kv9.1

Description (Vector)

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family.

Gene ID

3787

Gene Name (Vector)

potassium voltage-gated channel modifier subfamily S member 1

Gene Symbol

KCNS1

HGNC ID

HGNC:6300

ORF Size (aa)

1581

ORF Size (bp)

1581 bp

RefSeq ID

NM_002251

RefSeq Synonyms

NM_002251, NM_001322799, BC144234, BC132959, BC132957, BC075034, BC075033,

Species

human

UniGene ID

Hs.117780

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.