human KCNK4 shRNA silencing AAV

Name
AAV-h-KCNK4-shRNA

Cat No
shAAV-212747

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNK4.

shAAV-212747

AAV-h-KCNK4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNK4 (potassium two pore domain channel subfamily K member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

K2p4.1; TRAAK; TRAAK1

Description (Vector)

Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.

Gene ID

50801

Gene Name (Vector)

potassium two pore domain channel subfamily K member 4

Gene Symbol

KCNK4

HGNC ID

HGNC:6279

ORF Size (aa)

1182

ORF Size (bp)

1182 bp

RefSeq ID

NM_033310

RefSeq Synonyms

NM_033310, NM_001317090, BC160128, BC033577,

Species

human

UniGene ID

Hs.647233

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.