human KCNIP4 shRNA silencing AAV

Name
AAV-h-KCNIP4-shRNA

Cat No
shAAV-212707

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNIP4.

shAAV-212707

AAV-h-KCNIP4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNIP4 (potassium voltage-gated channel interacting protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CALP; KCHIP4

Description (Vector)

KCNIP4 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

80333

Gene Name (Vector)

potassium voltage-gated channel interacting protein 4

Gene Symbol

KCNIP4

HGNC ID

HGNC:30083

ORF Size (aa)

753

ORF Size (bp)

753 bp

RefSeq ID

NM_025221

RefSeq Synonyms

NM_147183, NM_147182, NM_147181, NM_025221, NM_001035004, NM_001035003, BC032520,

Species

human

UniGene ID

Hs.655705

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.