human KCNG3 shRNA silencing AAV

Name
AAV-h-KCNG3-shRNA

Cat No
shAAV-212693

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNG3.

shAAV-212693

AAV-h-KCNG3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNG3 (potassium voltage-gated channel modifier subfamily G member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

KV10.1; KV6.3

Description (Vector)

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.

Gene ID

170850

Gene Name (Vector)

potassium voltage-gated channel modifier subfamily G member 3

Gene Symbol

KCNG3

HGNC ID

HGNC:18306

ORF Size (aa)

1311

RefSeq ID

NM_133329

RefSeq Synonyms

NM_172344, NM_133329, BC071558,

Species

human

UniGene ID

Hs.352633

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.