human JMJD6 shRNA silencing AAV

Name 
AAV-h-JMJD6-shRNA
Cat No 
shAAV-212584
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human JMJD6.

shAAV-212584
AAV-h-JMJD6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human JMJD6 (arginine demethylase and lysine hydroxylase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
arginine demethylase and lysine hydroxylase; bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; histone arginine demethylase JMJD6; jmjC domain-containing protein 6; jumonji domain containing 6; jumonji domain-containing protein 6; lysyl-hydroxylase JMJD6; peptide-lysine 5-dioxygenase JMJD6; phosphatidylserine receptor; Protein PTDSR; PSR; PTDSR; PTDSR1
Description (eCommerce)
JMJD6 is a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. JMJD6 was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, [taken from NCBI Entrez Gene (Gene ID: 23210)].
Description (Vector)
JMJD6 encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
23210
Gene Name (eCommerce)
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
Gene Name (Vector)
arginine demethylase and lysine hydroxylase
Gene Symbol
JMJD6
HGNC ID
HGNC:19355
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1212
ORF Size (bp)
1212 bp
Protein Name (eCommerce)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
RefSeq ID
NM_015167
RefSeq Synonyms
NM_015167, NM_001081461, BC066654,
Research Areas
Angiogenesis,Apoptosis,Cardiac Development,Cardiology,Cardiovascular,Gene Expression,Histone Modification,Immunology,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Transcription Factor / Regulator
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,genetics,immunology,transcription_translation
Species
human
Target Sentence
JMJD6 is a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. JMJD6 was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, [taken from NCBI Entrez Gene (Gene ID: 23210)].
UniGene ID
Hs.514505
UniProt ID (eCommerce)
Q6NYC1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.