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human JDP2 shRNA silencing AAV

Name 
AAV-h-JDP2-shRNA
Cat No 
shAAV-212580
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human JDP2.

shAAV-212580
AAV-h-JDP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human JDP2 (Jun dimerization protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
jun dimerization protein 2; JUNDM2; progesterone receptor co-activator
Description (eCommerce)
JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. JDP2 is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYK2].
Gene ID
122953
Gene Name (eCommerce)
Jun dimerization protein 2
Gene Name (Vector)
Jun dimerization protein 2
Gene Symbol
JDP2
HGNC ID
HGNC:17546
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
492
ORF Size (bp)
492 bp
Protein Name (eCommerce)
Jun dimerization protein 2
RefSeq ID
NM_130469
RefSeq Synonyms
NM_130469, NM_001135049, NM_001135048, NM_001135047, BC051303,
Research Areas
Histone Modification,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. JDP2 is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYK2].
UniGene ID
Hs.196482
UniProt ID (eCommerce)
Q8WYK2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.