human IVD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IVD.
shAAV-212561
AAV-h-IVD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IVD (isovaleryl-CoA dehydrogenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACAD2
Description (Vector)
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3712
Gene Name (Vector)
isovaleryl-CoA dehydrogenase
Gene Symbol
IVD
HGNC ID
HGNC:6186
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_002225
RefSeq Synonyms
NM_002225, NM_001159508, BC017202,
Species
human
UniGene ID
Hs.513646
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.