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human ITPKA shRNA silencing AAV

Name 
AAV-h-ITPKA-shRNA
Cat No 
shAAV-212546
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ITPKA.

shAAV-212546
AAV-h-ITPKA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ITPKA (inositol-trisphosphate 3-kinase A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IP3-3KA; IP3KA
Description (Vector)
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
Gene ID
3706
Gene Name (Vector)
inositol-trisphosphate 3-kinase A
Gene Symbol
ITPKA
HGNC ID
HGNC:6178
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_002220
RefSeq Synonyms
NM_002220, BC026331,
Species
human
UniGene ID
Hs.2722

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.