human ITIH4 shRNA silencing AAV

Name 
AAV-h-ITIH4-shRNA
Cat No 
shAAV-212526
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ITIH4.

shAAV-212526
AAV-h-ITIH4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ITIH4 (inter-alpha-trypsin inhibitor heavy chain family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GP120; H4P; IHRP; ITI-HC4; ITIHL1; PK-120; PK120
Description (Vector)
ITIH4 is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
3700
Gene Name (Vector)
inter-alpha-trypsin inhibitor heavy chain family member 4
Gene Symbol
ITIH4
HGNC ID
HGNC:6169
ORF Size (aa)
2808
ORF Size (bp)
2808 bp
RefSeq ID
NM_002218
RefSeq Synonyms
NM_002218, NM_001166449, BC136393, BC136392,
Species
human
UniGene ID
Hs.709406

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.