human ITIH3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ITIH3.
shAAV-212522
AAV-h-ITIH3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ITIH3 (inter-alpha-trypsin inhibitor heavy chain 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H3P; ITI-HC3; SHAP
Description (Vector)
The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 (PubMed 2446322); Himmelfarb et al., 2004 (PubMed 14744536)).(supplied by OMIM, Nov 2009)
Gene ID
3699
Gene Name (Vector)
inter-alpha-trypsin inhibitor heavy chain 3
Gene Symbol
ITIH3
HGNC ID
HGNC:6168
ORF Size (aa)
2673
ORF Size (bp)
2673 bp
RefSeq ID
NM_002217
RefSeq Synonyms
NM_002217, BC107814, BC107605, BC107604,
Species
human
UniGene ID
Hs.76716
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.