human ITGB8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ITGB8.
shAAV-212518
AAV-h-ITGB8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ITGB8 (integrin subunit beta 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
ITGB8 is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Gene ID
3696
Gene Name (Vector)
integrin subunit beta 8
Gene Symbol
ITGB8
HGNC ID
HGNC:6163
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_002214
RefSeq Synonyms
NM_002214, BC002630,
Species
human
UniGene ID
Hs.592171
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.