human ISL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ISL1.
shAAV-212438
AAV-h-ISL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ISL1 (ISL LIM homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Isl-1; ISLET1
Description (Vector)
ISL1 encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Gene ID
3670
Gene Name (Vector)
ISL LIM homeobox 1
Gene Symbol
ISL1
HGNC ID
HGNC:6132
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_002202
RefSeq Synonyms
NM_002202, BC031213,
Species
human
UniGene ID
Hs.505
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.