human IRF6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IRF6.
shAAV-212411
AAV-h-IRF6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IRF6 (interferon regulatory factor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Description (Vector)
IRF6 encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Gene ID
3664
Gene Name (Vector)
interferon regulatory factor 6
Gene Symbol
IRF6
HGNC ID
HGNC:6121
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
RefSeq ID
NM_006147
RefSeq Synonyms
NM_006147, NM_001206696, BC014852,
Species
human
UniGene ID
Hs.591415
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.