human IP6K1 shRNA silencing AAV

Name
AAV-h-IP6K1-shRNA

Cat No
shAAV-212334

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human IP6K1.

shAAV-212334

AAV-h-IP6K1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IP6K1 (inositol hexakisphosphate kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ATP:1D-myo-inositol-hexakisphosphate phosphotransferase; IHPK1; inositol hexakisphosphate kinase 1; inositol hexaphosphate kinase 1; insP6 kinase 1; Pi uptake stimulator; PiUS

Description (eCommerce)

IP6K1 converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92551].

Description (Vector)

IP6K1 encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.

Gene ID

9807

Gene Name (eCommerce)

inositol hexakisphosphate kinase 1

Gene Name (Vector)

inositol hexakisphosphate kinase 1

Gene Symbol

IP6K1

HGNC ID

HGNC:18360

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1326

ORF Size (bp)

1326 bp

Protein Name (eCommerce)

Inositol hexakisphosphate kinase 1

RefSeq ID

NM_153273

RefSeq Synonyms

NM_153273, NM_001242829, NM_001006115, BC012944,

Research Areas

Metabolism/Metabolic Process

Research Areas (Faceted)

cell_biology,metabolism

Species

human

Target Sentence

IP6K1 converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92551].

UniGene ID

Hs.386168

UniProt ID (eCommerce)

Q92551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.