human ING5 shRNA silencing AAV

Name
AAV-h-ING5-shRNA

Cat No
shAAV-212268

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ING5.

shAAV-212268

AAV-h-ING5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ING5 (inhibitor of growth family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

p28ING5

Description (Vector)

ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.

Gene ID

84289

Gene Name (Vector)

inhibitor of growth family member 5

Gene Symbol

ING5

HGNC ID

HGNC:19421

ORF Size (aa)

681

RefSeq ID

NM_032329

RefSeq Synonyms

NM_032329, NM_001330162, NM_001330161, BC071899, BC005370,

Species

human

UniGene ID

Hs.645460

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.