human IL9R shRNA silencing AAV

Name
AAV-h-IL9R-shRNA

Cat No
shAAV-212221

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IL9R.

shAAV-212221

AAV-h-IL9R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL9R (interleukin 9 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD129; IL-9R

Description (Vector)

IL9R is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Gene ID

3581

Gene Name (Vector)

interleukin 9 receptor

Gene Symbol

IL9R

HGNC ID

HGNC:6030

ORF Size (aa)

999

ORF Size (bp)

999 bp

RefSeq ID

NM_002186

RefSeq Synonyms

NM_176786, NM_002186, BC051337,

Species

human

UniGene ID

Hs.406228

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.