human IL7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IL7.
shAAV-212206
AAV-h-IL7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IL7 (interleukin 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IL-7
Description (Vector)
IL7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Gene ID
3574
Gene Name (Vector)
interleukin 7
Gene Symbol
IL7
HGNC ID
HGNC:6023
ORF Size (aa)
534
RefSeq ID
NM_000880
RefSeq Synonyms
NM_001199888, NM_001199887, NM_001199886, NM_000880, BC047698,
Species
human
UniGene ID
Hs.591873
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.