human IL1RAP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IL1RAP.
shAAV-212110
AAV-h-IL1RAP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IL1RAP (interleukin 1 receptor accessory protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C3orf13; IL-1RAcP; IL1R3
Description (Vector)
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
Gene ID
3556
Gene Name (Vector)
interleukin 1 receptor accessory protein
Gene Symbol
IL1RAP
HGNC ID
HGNC:5995
ORF Size (aa)
1071
ORF Size (bp)
1071 bp
RefSeq ID
NM_002182
RefSeq Synonyms
NM_134470, NM_002182, NM_001167931, NM_001167930, NM_001167929, NM_001167928, BC053621,
Species
human
UniGene ID
Hs.478673
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.