human IKBKE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IKBKE.
shAAV-212009
AAV-h-IKBKE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IKBKE (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IKK-E; IKK-i; IKKE; IKKI
Description (Vector)
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 (PubMed 19481526)).(supplied by OMIM, Oct 2009)
Gene ID
9641
Gene Name (Vector)
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Gene Symbol
IKBKE
HGNC ID
HGNC:14552
ORF Size (aa)
2151
ORF Size (bp)
2151 bp
RefSeq ID
NM_014002
RefSeq Synonyms
NM_014002, NM_001193322, NM_001193321, BC107812, BC105924, BC105923,
Species
human
UniGene ID
Hs.321045
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.