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human IGSF8 shRNA silencing AAV

Name 
AAV-h-IGSF8-shRNA
Cat No 
shAAV-212001
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IGSF8.

shAAV-212001
AAV-h-IGSF8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IGSF8 (immunoglobulin superfamily member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD316; CD81P3; EWI-2; EWI2; KCT-4; LIR-D1; PGRL
Description (Vector)
IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
Gene ID
93185
Gene Name (Vector)
immunoglobulin superfamily member 8
Gene Symbol
IGSF8
HGNC ID
HGNC:17813
ORF Size (aa)
1842
ORF Size (bp)
1842 bp
RefSeq ID
NM_052868
RefSeq Synonyms
NM_052868, NM_001320247, NM_001206665, BC053881,
Species
human
UniGene ID
Hs.332012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.