human IGHMBP2 shRNA silencing AAV

Name 
AAV-h-IGHMBP2-shRNA
Cat No 
shAAV-211950
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IGHMBP2.

shAAV-211950
AAV-h-IGHMBP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IGHMBP2 (immunoglobulin mu binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CATF1; CMT2S; HCSA; HMN6; SMARD1; SMUBP2; ZFAND7
Description (Vector)
IGHMBP2 encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1.
Gene ID
3508
Gene Name (Vector)
immunoglobulin mu binding protein 2
Gene Symbol
IGHMBP2
HGNC ID
HGNC:5542
ORF Size (aa)
2982
ORF Size (bp)
2982 bp
RefSeq ID
NM_002180
RefSeq Synonyms
NM_002180, BC105090, BC105088,
Species
human
UniGene ID
Hs.503048

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.