human IFITM5 shRNA silencing AAV

Name 
AAV-h-IFITM5-shRNA
Cat No 
shAAV-211818
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IFITM5.

shAAV-211818
AAV-h-IFITM5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IFITM5 (interferon induced transmembrane protein 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BRIL; DSPA1; fragilis4; Hrmp1; OI5
Description (Vector)
IFITM5 encodes a membrane protein thought to play a role in bone mineralization. IFITM5 is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).
Gene ID
387733
Gene Name (Vector)
interferon induced transmembrane protein 5
Gene Symbol
IFITM5
HGNC ID
HGNC:16644
ORF Size (aa)
396
RefSeq ID
NM_001025295
RefSeq Synonyms
NM_001025295, BC156992, BC156100, BC150563, BC150562,
Species
human
UniGene ID
Hs.443469

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.