human IER3 shRNA silencing AAV

Name 
AAV-h-IER3-shRNA
Cat No 
shAAV-211784
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IER3.

shAAV-211784
AAV-h-IER3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IER3 (immediate early response 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DIF-2; DIF2; GLY96; IEX-1; IEX-1L; IEX1; PRG1
Description (Vector)
IER3 functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.
Gene ID
8870
Gene Name (Vector)
immediate early response 3
Gene Symbol
IER3
HGNC ID
HGNC:5392
ORF Size (aa)
471
RefSeq ID
NM_003897
RefSeq Synonyms
NM_003897, BC005080, BC000844,
Species
human
UniGene ID
Hs.591785

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.