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human ID2 shRNA silencing AAV

Name 
AAV-h-ID2-shRNA
Cat No 
shAAV-211763
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ID2.

shAAV-211763
AAV-h-ID2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ID2 (inhibitor of DNA binding 2, HLH protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHb26; GIG8; ID2A; ID2H
Description (Vector)
ID2 belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
Gene ID
3398
Gene Name (Vector)
inhibitor of DNA binding 2, HLH protein
Gene Symbol
ID2
HGNC ID
HGNC:5361
ORF Size (aa)
405
RefSeq ID
NM_002166
RefSeq Synonyms
NM_002166, BC030639,
Species
human
UniGene ID
Hs.180919

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.