human HTRA1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HTRA1.
shAAV-211713
AAV-h-HTRA1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HTRA1 (HtrA serine peptidase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
Description (Vector)
HTRA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
Gene ID
5654
Gene Name (Vector)
HtrA serine peptidase 1
Gene Symbol
HTRA1
HGNC ID
HGNC:9476
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
RefSeq ID
NM_002775
RefSeq Synonyms
NM_002775, BC172536, BC156552,
Species
human
UniGene ID
Hs.501280
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.