human HSD17B12 shRNA silencing AAV

Name 
AAV-h-HSD17B12-shRNA
Cat No 
shAAV-211570
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HSD17B12.

shAAV-211570
AAV-h-HSD17B12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KAR; SDR12C1
Description (Vector)
HSD17B12 encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation.
Gene ID
51144
Gene Name (Vector)
hydroxysteroid 17-beta dehydrogenase 12
Gene Symbol
HSD17B12
HGNC ID
HGNC:18646
ORF Size (aa)
939
ORF Size (bp)
939 bp
RefSeq ID
NM_016142
RefSeq Synonyms
NM_016142, BC012536, BC012043,
Species
human
UniGene ID
Hs.132513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.