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human HS2ST1 shRNA silencing AAV

Name 
AAV-h-HS2ST1-shRNA
Cat No 
shAAV-211533
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HS2ST1.

shAAV-211533
AAV-h-HS2ST1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HS2ST1 (heparan sulfate 2-O-sulfotransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ604K5.2
Description (Vector)
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.
Gene ID
9653
Gene Name (Vector)
heparan sulfate 2-O-sulfotransferase 1
Gene Symbol
HS2ST1
HGNC ID
HGNC:5193
ORF Size (aa)
690
ORF Size (bp)
690 bp
RefSeq ID
NM_012262
RefSeq Synonyms
NM_012262, NM_001134492, BC108735, BC025990, BC025384,
Species
human
UniGene ID
Hs.48823

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.