human DNASE1L3 Over-expression AAV

Name 
AAV-h-DNASE1L3
Cat No 
AAV-207191
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DNASE1L3.

AAV-207191
AAV-h-DNASE1L3

Ready-to-use AAV expressing Human DNASE1L3 (deoxyribonuclease 1 like 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DHP2; DNAS1L3; LSD; SLEB16
Description (Vector)
DNASE1L3 encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
1776
Gene Name (Vector)
deoxyribonuclease 1 like 3
Gene Symbol
DNASE1L3
HGNC ID
HGNC:2959
ORF Size (aa)
918
ORF Size (bp)
918 bp
RefSeq ID
NM_004944
RefSeq Synonyms
NM_004944, NM_001256560, BC015831,
Species
human
UniGene ID
Hs.476453

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.