human HPSE2 shRNA silencing AAV

Name 
AAV-h-HPSE2-shRNA
Cat No 
shAAV-211509
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HPSE2.

shAAV-211509
AAV-h-HPSE2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HPSE2 (heparanase 2 (inactive)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HPA2; HPR2; UFS; UFS1
Description (Vector)
HPSE2 encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
Gene ID
60495
Gene Name (Vector)
heparanase 2 (inactive)
Gene Symbol
HPSE2
HGNC ID
HGNC:18374
ORF Size (aa)
1779
ORF Size (bp)
1779 bp
RefSeq ID
NM_021828
RefSeq Synonyms
NM_021828, NM_001166246, NM_001166245, NM_001166244, BC112356,
Species
human
UniGene ID
Hs.500750

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.