human HPD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HPD.
shAAV-211497
AAV-h-HPD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HPD (4-hydroxyphenylpyruvate dioxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD
Description (Vector)
HPD is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
3242
Gene Name (Vector)
4-hydroxyphenylpyruvate dioxygenase
Gene Symbol
HPD
HGNC ID
HGNC:5147
ORF Size (aa)
1182
ORF Size (bp)
1182 bp
RefSeq ID
NM_002150
RefSeq Synonyms
NM_002150, NM_001171993, BC024287,
Species
human
UniGene ID
Hs.2899
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.