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human HOXC10 shRNA silencing AAV

Name 
AAV-h-HOXC10-shRNA
Cat No 
shAAV-211462
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HOXC10.

shAAV-211462
AAV-h-HOXC10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HOXC10 (homeobox C10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
homeo box C10; homeobox protein Hox-3I; homeobox protein Hox-C10; homeoprotein C10; HOX3I
Description (eCommerce)
Homeobox C10 (HOXC10) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation [taken from NCBI Entrez Gene (Gene ID: 3226)].
Description (Vector)
HOXC10 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. HOXC10 is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.
Gene ID
3226
Gene Name (eCommerce)
homeobox C10
Gene Name (Vector)
homeobox C10
Gene Symbol
HOXC10
HGNC ID
HGNC:5122
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1029
ORF Size (bp)
1029 bp
Protein Name (eCommerce)
Homeobox protein Hox-C10
RefSeq ID
NM_017409
RefSeq Synonyms
NM_017409, BC001293,
Research Areas
Neurobiology,Neurodevelopment,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology,transcription_translation
Species
human
Target Sentence
Homeobox C10 (HOXC10) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation [taken from NCBI Entrez Gene (Gene ID: 3226)].
UniGene ID
Hs.44276
UniProt ID (eCommerce)
Q9NYD6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.