human HNRNPR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HNRNPR.
shAAV-211385
AAV-h-HNRNPR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HNRNPR (heterogeneous nuclear ribonucleoprotein R). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hnRNP-R; HNRPR
Description (Vector)
HNRNPR belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
10236
Gene Name (Vector)
heterogeneous nuclear ribonucleoprotein R
Gene Symbol
HNRNPR
HGNC ID
HGNC:5047
ORF Size (aa)
1911
ORF Size (bp)
1911 bp
RefSeq ID
NM_005826
RefSeq Synonyms
NM_005826, NM_001297622, NM_001297621, NM_001297620, NM_001102399, NM_001102398, NM_001102397, BC001449,
Species
human
UniGene ID
Hs.373763
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.