human HIST1H2AD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HIST1H2AD.
shAAV-211068
AAV-h-HIST1H2AD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HIST1H2AD (histone cluster 1 H2A family member d). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H2A.3; H2A/g; H2AFG
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Gene ID
3013
Gene Name (Vector)
histone cluster 1 H2A family member d
Gene Symbol
HIST1H2AD
HGNC ID
HGNC:4729
ORF Size (aa)
393
RefSeq ID
NM_021065
RefSeq Synonyms
NM_021065, BC128035, BC093809, BC093807,
Species
human
UniGene ID
Hs.679229
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.