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human HIST1H1D shRNA silencing AAV

Name 
AAV-h-HIST1H1D-shRNA
Cat No 
shAAV-211057
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HIST1H1D.

shAAV-211057
AAV-h-HIST1H1D-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HIST1H1D (histone cluster 1 H1 family member d). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
H1.3; H1D; H1F3; H1s-2
Description (Vector)
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Gene ID
3007
Gene Name (Vector)
histone cluster 1 H1 family member d
Gene Symbol
HIST1H1D
HGNC ID
HGNC:4717
ORF Size (aa)
666
ORF Size (bp)
666 bp
RefSeq ID
NM_005320
RefSeq Synonyms
NM_005320, BC111971, BC104874,
Species
human
UniGene ID
Hs.136857

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.