human HINT1 shRNA silencing AAV

Name
AAV-h-HINT1-shRNA

Cat No
shAAV-211034

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human HINT1.

shAAV-211034

AAV-h-HINT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HINT1 (histidine triad nucleotide binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

adenosine 5'-monophosphoramidase; epididymis secretory sperm binding protein; HINT; histidine triad nucleotide-binding protein 1; NMAN; PKCI-1; PRKCNH1; protein kinase C inhibitor 1; protein kinase C-interacting protein 1

Description (eCommerce)

Histidine triad nucleotide-binding protein 1 (HINT1) hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif [taken from NCBI Entrez Gene (Gene ID: 3094)].

Gene ID

3094

Gene Name (eCommerce)

histidine triad nucleotide binding protein 1

Gene Name (Vector)

histidine triad nucleotide binding protein 1

Gene Symbol

HINT1

HGNC ID

HGNC:4912

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

381

ORF Size (bp)

381 bp

Protein Name (eCommerce)

Histidine triad nucleotide-binding protein 1

RefSeq ID

NM_005340

RefSeq Synonyms

NM_005340, BC007090, BC001287,

Research Areas

Apoptosis,Cytoskeleton,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,developmental_biology,neurobiology,signal_transduction,transcription_translation

Species

human

Target Sentence

Histidine triad nucleotide-binding protein 1 (HINT1) hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif [taken from NCBI Entrez Gene (Gene ID: 3094)].

UniGene ID

Hs.483305

UniProt ID (eCommerce)

P49773

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.