human HIF3A shRNA silencing AAV

Name 
AAV-h-HIF3A-shRNA
Cat No 
shAAV-211022
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HIF3A.

shAAV-211022
AAV-h-HIF3A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HIF3A (hypoxia inducible factor 3 alpha subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
Description (Vector)
HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
64344
Gene Name (Vector)
hypoxia inducible factor 3 alpha subunit
Gene Symbol
HIF3A
HGNC ID
HGNC:15825
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
RefSeq ID
NM_022462
RefSeq Synonyms
NM_152796, NM_152795, NM_152794, NM_022462, BC080551, BC026308,
Species
human
UniGene ID
Hs.420830

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.