human HEPN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HEPN1.
shAAV-210951
AAV-h-HEPN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HEPN1 (hepatocellular carcinoma, down-regulated 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
HEPN1 is expressed in the liver, and encodes a short peptide that is localized predominantly to the cytoplasm. Transient transfection studies showed that expression of this gene significantly inhibited cell growth, and it may have a role in apoptosis. Expression of this gene is downregulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). Also to note is that this gene maps to the 3'-noncoding region of HEPACAM gene (GeneID:220296) on the antisense strand (PMID:15885354).
Gene ID
641654
Gene Name (Vector)
hepatocellular carcinoma, down-regulated 1
Gene Symbol
HEPN1
HGNC ID
HGNC:34400
ORF Size (aa)
267
RefSeq ID
NM_001037558
RefSeq Synonyms
NM_001037558, BC156583, BC148521,
Species
human
UniGene ID
Hs.159863
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.