human HCRT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HCRT.
shAAV-210877
AAV-h-HCRT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HCRT (hypocretin neuropeptide precursor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NRCLP1; OX; PPOX
Description (Vector)
HCRT encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
Gene ID
3060
Gene Name (Vector)
hypocretin neuropeptide precursor
Gene Symbol
HCRT
HGNC ID
HGNC:4847
ORF Size (aa)
393
RefSeq ID
NM_001524
RefSeq Synonyms
NM_001524, BC111915,
Species
human
UniGene ID
Hs.158348
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.