human HCK shRNA silencing AAV

Name 
AAV-h-HCK-shRNA
Cat No 
shAAV-210863
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HCK.

shAAV-210863
AAV-h-HCK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HCK (HCK proto-oncogene, Src family tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
JTK9; p59Hck; p61Hck
Description (Vector)
HCK is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Gene ID
3055
Gene Name (Vector)
HCK proto-oncogene, Src family tyrosine kinase
Gene Symbol
HCK
HGNC ID
HGNC:4840
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_002110
RefSeq Synonyms
NM_002110, NM_001172133, NM_001172132, NM_001172131, NM_001172130, NM_001172129, BC114463, BC113854, BC108931, BC108930, BC094847, BC014435,
Species
human
UniGene ID
Hs.655210

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.