human HAX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HAX1.
shAAV-210811
AAV-h-HAX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HAX1 (HCLS1 associated protein X-1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HCLSBP1; HS1BP1; SCN3
Description (Vector)
HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10456
Gene Name (Vector)
HCLS1 associated protein X-1
Gene Symbol
HAX1
HGNC ID
HGNC:16915
ORF Size (aa)
840
ORF Size (bp)
840 bp
RefSeq ID
NM_006118
RefSeq Synonyms
NM_006118, NM_001018837, BC016730, BC015209, BC014314, BC005240,
Species
human
UniGene ID
Hs.199625
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.