human GUCY1A3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GUCY1A3.
shAAV-210688
AAV-h-GUCY1A3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GUCY1A3 (guanylate cyclase 1 soluble subunit alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; MYMY6
Description (Vector)
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene ID
2982
Gene Name (Vector)
guanylate cyclase 1 soluble subunit alpha
Gene Symbol
GUCY1A3
HGNC ID
HGNC:4685
ORF Size (aa)
2073
ORF Size (bp)
2073 bp
RefSeq ID
NM_000856
RefSeq Synonyms
NM_001256449, NM_001130687, NM_001130686, NM_001130685, NM_001130684, NM_001130683, NM_001130682, NM_000856, BC028384, BC012627,
Species
human
UniGene ID
Hs.24258
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.