human GTPBP3 shRNA silencing AAV

Name 
AAV-h-GTPBP3-shRNA
Cat No 
shAAV-210663
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GTPBP3.

shAAV-210663
AAV-h-GTPBP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GTPBP3 (GTP binding protein 3 (mitochondrial)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COXPD23; GTPBG3; MSS1; MTGP1; THDF1
Description (Vector)
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
84705
Gene Name (Vector)
GTP binding protein 3 (mitochondrial)
Gene Symbol
GTPBP3
HGNC ID
HGNC:14880
ORF Size (aa)
1479
ORF Size (bp)
1479 bp
RefSeq ID
NM_032620
RefSeq Synonyms
NM_133644, NM_032620, NM_001195422, NM_001128855, BC019261, BC017207,
Species
human
UniGene ID
Hs.334885

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.