human GTF2IRD2 shRNA silencing AAV

Name
AAV-h-GTF2IRD2-shRNA

Cat No
shAAV-210651

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GTF2IRD2.

shAAV-210651

AAV-h-GTF2IRD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GTF2IRD2 (GTF2I repeat domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FP630; GTF2IRD2 alpha; GTF2IRD2A

Description (Vector)

GTF2IRD2 is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. However, there is mRNA and EST evidence to suggest that this gene is transcribed, and the encoded protein has a homolog in mouse, with which it shares 78% sequence identity. The exact function of this gene product is not known. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. These three genes are clustered together on chr 7q11.23.

Gene ID

84163

Gene Name (Vector)

GTF2I repeat domain containing 2

Gene Symbol

GTF2IRD2

HGNC ID

HGNC:30775

ORF Size (aa)

1497

ORF Size (bp)

1497 bp

RefSeq ID

NM_173537

RefSeq Synonyms

NM_173537, NM_001281447, BC067859, BC047706,

Species

human

UniGene ID

Hs.647039

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.