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human GRXCR1 shRNA silencing AAV

Name 
AAV-h-GRXCR1-shRNA
Cat No 
shAAV-210571
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GRXCR1.

shAAV-210571
AAV-h-GRXCR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GRXCR1 (glutaredoxin and cysteine rich domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DFNB25; PPP1R88
Description (Vector)
GRXCR1 is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. GRXCR1 encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells.
Gene ID
389207
Gene Name (Vector)
glutaredoxin and cysteine rich domain containing 1
Gene Symbol
GRXCR1
HGNC ID
HGNC:31673
ORF Size (aa)
873
ORF Size (bp)
873 bp
RefSeq ID
NM_001080476
RefSeq Synonyms
NM_001080476, BC153209, BC148672,
Species
human
UniGene ID
Hs.162559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.