human GRB14 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GRB14.
shAAV-210488
AAV-h-GRB14-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GRB14 (growth factor receptor bound protein 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.
Gene ID
2888
Gene Name (Vector)
growth factor receptor bound protein 14
Gene Symbol
GRB14
HGNC ID
HGNC:4565
ORF Size (aa)
1623
ORF Size (bp)
1623 bp
RefSeq ID
NM_004490
RefSeq Synonyms
NM_004490, NM_001303422, BC053559,
Species
human
UniGene ID
Hs.411881
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.