human GPRC5A shRNA silencing AAV

Name 
AAV-h-GPRC5A-shRNA
Cat No 
shAAV-210426
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GPRC5A.

shAAV-210426
AAV-h-GPRC5A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GPRC5A (G protein-coupled receptor class C group 5 member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPCR5A; G-protein coupled receptor family C group 5 member A; orphan G-protein-coupling receptor PEIG-1; PEIG-1; phorbol ester induced gene 1; phorbol ester induced protein-1; RAI3; RAIG1; RAIG-1; retinoic acid induced 3; retinoic acid responsive; retinoic acid-induced gene 1 protein; retinoic acid-induced protein 3; TIG1; TPA induced gene 1
Description (eCommerce)
G-protein coupled receptor family C group 5 member A (GPRC5A) is a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 9052)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NFJ5].
Description (Vector)
GPRC5A encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. GPRC5A may play a role in embryonic development and epithelial cell differentiation.
Gene ID
9052
Gene Name (eCommerce)
G protein-coupled receptor class C group 5 member A
Gene Name (Vector)
G protein-coupled receptor class C group 5 member A
Gene Symbol
GPRC5A
HGNC ID
HGNC:9836
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1074
ORF Size (bp)
1074 bp
Protein Name (eCommerce)
Retinoic acid-induced protein 3
RefSeq ID
NM_003979
RefSeq Synonyms
NM_003979, BC003665,
Research Areas
Cancer,EGFR Signaling,Golgi Apparatus,Signal Transduction
Research Areas (Faceted)
cancer,signal_transduction,cell_biology
Species
human
Target Sentence
G-protein coupled receptor family C group 5 member A (GPRC5A) is a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 9052)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NFJ5].
UniGene ID
Hs.631733
UniProt ID (eCommerce)
Q8NFJ5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.