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human GPR112 shRNA silencing AAV

Name 
AAV-h-GPR112-shRNA
Cat No 
shAAV-210257
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ADGRG4.

shAAV-210257
AAV-h-GPR112-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADGRG4 (adhesion G protein-coupled receptor G4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPR112; PGR17; RP1-299I16
Description (Vector)
GPR112 encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy.
Gene ID
139378
Gene Name (Vector)
adhesion G protein-coupled receptor G4
Gene Symbol
ADGRG4
ORF Size (aa)
9240
ORF Size (bp)
9240 bp
RefSeq ID
NM_153834
RefSeq Synonyms
NM_153834, BC156126,
Species
human
UniGene ID
Hs.381354

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.